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The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation
Hypoxia is widely considered as a limiting factor in vertebrate embryonic development, which requires adequate oxygen delivery for efficient energy metabolism, while nowadays some researches have revealed that hypoxia can induce stem cells so as to improve embryonic development. Erythroid differenti...
Autores principales: | Wang, Yiqin, Liu, Xiaohui, Xie, Baoshu, Yuan, Hao, Zhang, Yiyue, Zhu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812007/ https://www.ncbi.nlm.nih.gov/pubmed/31539803 http://dx.doi.org/10.1016/j.redox.2019.101313 |
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