DNA damage and synaptic and behavioural disorders in glucose-6-phosphate dehydrogenase-deficient mice()

Mice deficient in glucose-6-phosphate dehydrogenase (G6PD) cannot replenish the cellular antioxidant glutathione, which detoxifies neurodegenerative reactive oxygen species (ROS). To determine the functional consequences of G6PD deficiency, young and aging G6PD-deficient mice were evaluated for brai...

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Detalles Bibliográficos
Autores principales: Loniewska, Margaret M., Gupta, Anmol, Bhatia, Shama, MacKay-Clackett, Isabel, Jia, Zhengping, Wells, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812046/
https://www.ncbi.nlm.nih.gov/pubmed/31581069
http://dx.doi.org/10.1016/j.redox.2019.101332

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