Modulation of FLT3 signal transduction through cytoplasmic cysteine residues indicates the potential for redox regulation

Oxidative modification of cysteine residues has been shown to regulate the activity of several protein-tyrosine kinases. We explored the possibility that Fms-like tyrosine kinase 3 (FLT3), a hematopoietic receptor-tyrosine kinase, is subject to this type of regulation. An underlying rationale was th...

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Detalles Bibliográficos
Autores principales: Böhmer, Annette, Barz, Saskia, Schwab, Katjana, Kolbe, Ulrike, Gabel, Anke, Kirkpatrick, Joanna, Ohlenschläger, Oliver, Görlach, Matthias, Böhmer, Frank-D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812047/
https://www.ncbi.nlm.nih.gov/pubmed/31606550
http://dx.doi.org/10.1016/j.redox.2019.101325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812047/
https://www.ncbi.nlm.nih.gov/pubmed/31606550
http://dx.doi.org/10.1016/j.redox.2019.101325

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