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Modulation of FLT3 signal transduction through cytoplasmic cysteine residues indicates the potential for redox regulation
Oxidative modification of cysteine residues has been shown to regulate the activity of several protein-tyrosine kinases. We explored the possibility that Fms-like tyrosine kinase 3 (FLT3), a hematopoietic receptor-tyrosine kinase, is subject to this type of regulation. An underlying rationale was th...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812047/ https://www.ncbi.nlm.nih.gov/pubmed/31606550 http://dx.doi.org/10.1016/j.redox.2019.101325 |