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Discovery of Dihydropyrrol-2-ones as Novel G0/G1-Phase Arresting Agents Inducing Apoptosis

[Image: see text] A series of dihydropyrrol-2-ones (DHPs) were designed and synthesized via an efficient multicomponent reaction at room temperature for evaluation of their bioactivities against four human cancer lines (MCF-7, RKO, HeLa, and A549) in vitro. Preliminary structure–activity relationshi...

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Detalles Bibliográficos
Autores principales:	Yang, Danni, Huang, Cuihong, Liao, Hui, Zhang, Huiwu, Wu, Shaoyu, Zhu, Qiuhua, Zhou, Zhong-Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812110/ https://www.ncbi.nlm.nih.gov/pubmed/31656929 http://dx.doi.org/10.1021/acsomega.9b02543

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