Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration

The retinal pigment epithelium (RPE) is consistently exposed to high levels of pro-oxidant and inflammatory stimuli. As such, under normal conditions the antioxidant machinery in the RPE cell is one of the most efficient in the entire body. However, antioxidant defense mechanisms are often impacted...

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Detalles Bibliográficos
Autores principales: Jadeja, Ravirajsinh N., Jones, Malita A., Abdelrahman, Ammar A., Powell, Folami L., Thounaojam, Menaka C., Gutsaeva, Diana, Bartoli, Manuela, Martin, Pamela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812120/
https://www.ncbi.nlm.nih.gov/pubmed/31590045
http://dx.doi.org/10.1016/j.redox.2019.101336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812120/
https://www.ncbi.nlm.nih.gov/pubmed/31590045
http://dx.doi.org/10.1016/j.redox.2019.101336

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