Long-term spontaneous remission with active surveillance in IgG4-related pleuritis: A case report and literature review

Pleural effusion is a relatively rare feature of IgG4-related disease (IgG4-RD). Here, we report a case of a 72-year-old woman who presented with pleural effusion. Although the pleural adenosine deaminase level was increased, surgical biopsy of the pleura and left inguinal lymph node indicated that...

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Detalles Bibliográficos
Autores principales: Makimoto, Go, Ohashi, Kadoaki, Taniguchi, Kohei, Soh, Junichi, Taniguchi, Akihiko, Miyahara, Nobuaki, Toyooka, Shinichi, Yoshino, Tadashi, Maeda, Yoshinobu, Kiura, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812137/
https://www.ncbi.nlm.nih.gov/pubmed/31667074
http://dx.doi.org/10.1016/j.rmcr.2019.100938
Descripción
Sumario:Pleural effusion is a relatively rare feature of IgG4-related disease (IgG4-RD). Here, we report a case of a 72-year-old woman who presented with pleural effusion. Although the pleural adenosine deaminase level was increased, surgical biopsy of the pleura and left inguinal lymph node indicated that the effusion was due to IgG4-RD. Active surveillance was initiated because serum IgG4 and pleural effusion naturally decreased and then completely disappeared. The patient has shown no recurrence for >4 years. This case suggests that pleural biopsy can be used to distinguish IgG4-RD from tuberculosis; moreover, some cases with pleural effusion could improve without treatment.

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