Cargando…
Identification of Fatty Acid Binding Protein 5 Inhibitors Through Similarity-Based Screening
[Image: see text] Fatty acid binding protein 5 (FABP5) is a promising target for development of inhibitors to help control pain and inflammation. In this work, computer-based docking (DOCK6 program) was employed to screen ∼2 M commercially available compounds to FABP5 based on an X-ray structure com...
Autores principales: | Zhou, Yuchen, Elmes, Matthew W., Sweeney, Joseph M., Joseph, Olivia M., Che, Joyce, Hsu, Hao-Chi, Li, Huilin, Deutsch, Dale G., Ojima, Iwao, Kaczocha, Martin, Rizzo, Robert C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812325/ https://www.ncbi.nlm.nih.gov/pubmed/31539229 http://dx.doi.org/10.1021/acs.biochem.9b00625 |
Ejemplares similares
-
Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia
por: Kaczocha, Martin, et al.
Publicado: (2014) -
Incarvillateine produces antinociceptive and motor suppressive effects via adenosine receptor activation
por: Kim, Jinwoo, et al.
Publicado: (2019) -
Fatty-acid-binding protein inhibition produces analgesic effects through peripheral and central mechanisms
por: Peng, Xiaoxue, et al.
Publicado: (2017) -
Targeting Fatty Acid Binding Protein (FABP) Anandamide Transporters – A Novel Strategy for Development of Anti-Inflammatory and Anti-Nociceptive Drugs
por: Berger, William T., et al.
Publicado: (2012) -
Fatty acid binding protein 5 regulates docetaxel sensitivity in taxane-resistant prostate cancer cells
por: Hillowe, Andrew, et al.
Publicado: (2023)