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Ghrelin-Induced Sodium Reabsorption Is Mediated by PKA and Microtubule-Dependent αE(Na)C Translocation in Female Rats

Intrarenal ghrelin infusion activates ghrelin receptors in the kidney collecting duct (CD) to increase α epithelial sodium (Na(+)) channel (αE(Na)C)-dependent Na(+) reabsorption in vivo, but the underlying mechanisms are unknown. Seventy-two hours following uninephrectomy, 12-week-old female Sprague...

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Detalles Bibliográficos
Autores principales: Kemp, Brandon A, Howell, Nancy L, Gildea, John J, Padia, Shetal H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812736/
https://www.ncbi.nlm.nih.gov/pubmed/31663064
http://dx.doi.org/10.1210/js.2019-00121