Cargando…

Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals

Studies have demonstrated that intensive ART alone is not capable of eradicating HIV-1, as the virus rebounds within a few weeks upon treatment interruption. Viral rebound may be induced from several cellular subsets; however, the majority of proviral DNA has been found in antigen experienced restin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wonderlich, Elizabeth R., Subramanian, Krupa, Cox, Bryan, Wiegand, Ann, Lackman-Smith, Carol, Bale, Michael J., Stone, Mars, Hoh, Rebecca, Kearney, Mary F., Maldarelli, Frank, Deeks, Steven G., Busch, Michael P., Ptak, Roger G., Kulpa, Deanna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812841/
https://www.ncbi.nlm.nih.gov/pubmed/31609991
http://dx.doi.org/10.1371/journal.ppat.1008074