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Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
Studies have demonstrated that intensive ART alone is not capable of eradicating HIV-1, as the virus rebounds within a few weeks upon treatment interruption. Viral rebound may be induced from several cellular subsets; however, the majority of proviral DNA has been found in antigen experienced restin...
Autores principales: | Wonderlich, Elizabeth R., Subramanian, Krupa, Cox, Bryan, Wiegand, Ann, Lackman-Smith, Carol, Bale, Michael J., Stone, Mars, Hoh, Rebecca, Kearney, Mary F., Maldarelli, Frank, Deeks, Steven G., Busch, Michael P., Ptak, Roger G., Kulpa, Deanna A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812841/ https://www.ncbi.nlm.nih.gov/pubmed/31609991 http://dx.doi.org/10.1371/journal.ppat.1008074 |
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