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Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing

During meiosis, each chromosome must selectively pair and synapse with its own unique homolog to enable crossover formation and subsequent segregation. How homolog pairing is maintained in early meiosis to ensure synapsis occurs exclusively between homologs is unknown. We aimed to further understand...

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Detalles Bibliográficos
Autores principales: Hatkevich, Talia, Boudreau, Vincent, Rubin, Thomas, Maddox, Paul S., Huynh, Jean-René, Sekelsky, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812850/
https://www.ncbi.nlm.nih.gov/pubmed/31609962
http://dx.doi.org/10.1371/journal.pgen.1008412