Phylogenetic correlations can suffice to infer protein partners from sequences

Determining which proteins interact together is crucial to a systems-level understanding of the cell. Recently, algorithms based on Direct Coupling Analysis (DCA) pairwise maximum-entropy models have allowed to identify interaction partners among paralogous proteins from sequence data. This success...

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Detalles Bibliográficos
Autores principales: Marmier, Guillaume, Weigt, Martin, Bitbol, Anne-Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812855/
https://www.ncbi.nlm.nih.gov/pubmed/31609984
http://dx.doi.org/10.1371/journal.pcbi.1007179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812855/
https://www.ncbi.nlm.nih.gov/pubmed/31609984
http://dx.doi.org/10.1371/journal.pcbi.1007179

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