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Thymically-derived Foxp3(+) regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model
Regulatory T cells (Tregs) are an immunosuppressive population that are identified based on the stable expression of the fate-determining transcription factor forkhead box P3 (Foxp3). Tregs can be divided into distinct subsets based on whether they developed in the thymus (tTregs) or in the peripher...
| Auteurs principaux: | , , |
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| Format: | Online Article Texte |
| Langue: | English |
| Publié: |
Public Library of Science
2019
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| Accès en ligne: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812862/ https://www.ncbi.nlm.nih.gov/pubmed/31647813 http://dx.doi.org/10.1371/journal.pone.0217728 |