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Thymically-derived Foxp3(+) regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model

Regulatory T cells (Tregs) are an immunosuppressive population that are identified based on the stable expression of the fate-determining transcription factor forkhead box P3 (Foxp3). Tregs can be divided into distinct subsets based on whether they developed in the thymus (tTregs) or in the peripher...

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Bibliografske podrobnosti
Autores principales: Holohan, Daniel R., Van Gool, Frédéric, Bluestone, Jeffrey A.
Format: Online Artículo Texto
Jezik:English
Izdano: Public Library of Science 2019
Teme:
Online dostop:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6812862/
https://www.ncbi.nlm.nih.gov/pubmed/31647813
http://dx.doi.org/10.1371/journal.pone.0217728