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Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines

BACKGROUND: In mammalian cells, Aurora serine/threonine kinases (Aurora A, B, and C) are expressed in a cell cycle-dependent fashion as key mitotic regulators required for the maintenance of chromosomal stability. Aurora-A (AURKA) has been proven to be an oncogene in a variety of cancers; however, w...

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Detalles Bibliográficos
Autores principales:	Liu, Ningbo, Wang, Yong Antican, Sun, Yunguang, Ecsedy, Jeffrey, Sun, Jifeng, Li, Xue, Wang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813099/ https://www.ncbi.nlm.nih.gov/pubmed/31647033 http://dx.doi.org/10.1186/s12931-019-1194-8

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