Cargando…

Methionyl-tRNA Synthetase is a Useful Diagnostic Marker for Lymph Node Metastasis in Non-Small Cell Lung Cancer

PURPOSE: Identification of lymph node (LN) metastasis in non-small cell lung cancer (NSCLC) is critical for disease staging and selection of therapeutic modalities. Sometimes it is not possible to obtain LN core tissue by endobronchial ultrasound-guided transbronchial needle aspirate (EBUS-TBNA), re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jung Mo, Kim, Taehee, Kim, Eun Young, Kim, Arum, Lee, Dong Ki, Kwon, Nam Hoon, Kim, Sunghoon, Chang, Yoon Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813140/ https://www.ncbi.nlm.nih.gov/pubmed/31637881 http://dx.doi.org/10.3349/ymj.2019.60.11.1005

Ejemplares similares

Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes
por: Kim, Dong Kyu, et al.
Publicado: (2021)

Promiscuous methionyl-tRNA synthetase mediates adaptive mistranslation to protect cells against oxidative stress
por: Lee, Jin Young, et al.
Publicado: (2014)

Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila
por: Suh, Yoon Seok, et al.
Publicado: (2020)

Methionyl-tRNA synthetase overexpression is associated with poor clinical outcomes in non-small cell lung cancer
por: Kim, Eun Young, et al.
Publicado: (2017)

Nucleolar Localization of Human Methionyl–Trna Synthetase and Its Role in Ribosomal RNA Synthesis
por: Ko, Young-Gyu, et al.
Publicado: (2000)

Prediction of Prognosis in Pancreatic Cancer According to Methionyl-tRNA Synthetase 1 Expression as Determined by Immunohistochemical Staining
por: Jang, Sung Ill, et al.
Publicado: (2023)

Is Methionyl-tRNA Synthetase Applicable as a Diagnostic Marker for Lung Cancer in Bronchial Ultrasound-Guided Brushing Cells?
por: Lee, Kyungjong, et al.
Publicado: (2021)

let-65 is cytoplasmic methionyl tRNA synthetase in C. elegans
por: Alriyami, Maha Z., et al.
Publicado: (2014)

Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase
por: Torrie, Leah S., et al.
Publicado: (2020)

Methionyl-tRNA synthetase novel mutation causes pulmonary alveolar proteinosis
por: Alzaid, Mohammed, et al.
Publicado: (2019)

Association of methionyl-tRNA synthetase with detergent-insoluble components of the rough endoplasmic reticulum
Publicado: (1983)

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani
por: Torrie, Leah S., et al.
Publicado: (2017)

High methionyl–tRNA synthetase expression predicts poor prognosis in patients with breast cancer
por: Jin, Qin, et al.
Publicado: (2020)

Characterization of the Secretome of a Specific Cell Expressing Mutant Methionyl-tRNA Synthetase in Co-Culture Using Click Chemistry
por: Shin, Sungho, et al.
Publicado: (2022)

Aminoacyl-tRNA synthetases, therapeutic targets for infectious diseases
por: Lee, Eun-Young, et al.
Publicado: (2018)

Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
por: Ojo, Kayode K., et al.
Publicado: (2016)

Identifying potential natural inhibitors of Brucella melitensis Methionyl-tRNA synthetase through an in-silico approach
por: Rowaiye, Adekunle Babajide, et al.
Publicado: (2022)

Cancer Association Study of Aminoacyl-tRNA Synthetase Signaling Network in Glioblastoma
por: Kim, Yong-Wan, et al.
Publicado: (2012)

Rare recessive loss-of-function methionyl-tRNA synthetase mutations presenting as a multi-organ phenotype
por: van Meel, Eline, et al.
Publicado: (2013)

Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis
por: Ojo, Kayode K., et al.
Publicado: (2016)

Functional and pathologic association of aminoacyl-tRNA synthetases with cancer
por: Sung, Yulseung, et al.
Publicado: (2022)

Reactive oxygen species modulator 1 expression predicts lymph node metastasis and survival in early-stage non-small cell lung cancer
por: Kim, Taehee, et al.
Publicado: (2020)

Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness
por: Koh, Cho Yeow, et al.
Publicado: (2014)

Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex
por: Kim, Kyung Rok, et al.
Publicado: (2013)

Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes from cancer cells
por: Kim, Sang Bum, et al.
Publicado: (2017)

Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium
por: Mercaldi, Gustavo Fernando, et al.
Publicado: (2021)

Mutations in the Mitochondrial Methionyl-tRNA Synthetase Cause a Neurodegenerative Phenotype in Flies and a Recessive Ataxia (ARSAL) in Humans
por: Bayat, Vafa, et al.
Publicado: (2012)

Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis
por: Song, Dae-Geun, et al.
Publicado: (2018)

Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer
por: Kim, Eun Young, et al.
Publicado: (2019)

A threonyl-tRNA synthetase-mediated translation initiation machinery
por: Jeong, Seung Jae, et al.
Publicado: (2019)

Inhibition of MUC1 biosynthesis via threonyl-tRNA synthetase suppresses pancreatic cancer cell migration
por: Jeong, Seung Jae, et al.
Publicado: (2018)

Novel methionyl-tRNA synthetase gene variants/phenotypes in interstitial lung and liver disease: A case report and review of literature
por: Abuduxikuer, Kuerbanjiang, et al.
Publicado: (2018)

Prognostic value of expression of molecular markers in adenoid cystic cancer of the salivary glands compared with lymph node metastasis: a retrospective study
por: Lee, Seok Ki, et al.
Publicado: (2012)

Protocol for improving diffraction quality of leucyl-tRNA synthetase 1 with methylation and post-crystallization soaking and cooling in cryoprotectants
por: Kim, Sulhee, et al.
Publicado: (2021)

Treatment outcomes of extended-field radiation therapy and the effect of concurrent chemotherapy on uterine cervical cancer with para-aortic lymph node metastasis
por: Yoon, Hong In, et al.
Publicado: (2015)

5-Fluoroimidazo[4,5-b]pyridine Is a Privileged Fragment That Conveys Bioavailability to Potent Trypanosomal Methionyl-tRNA Synthetase Inhibitors
por: Zhang, Zhongsheng, et al.
Publicado: (2016)

Structural characterization of free-state and product-state Mycobacterium tuberculosis methionyl-tRNA synthetase reveals an induced-fit ligand-recognition mechanism
por: Wang, Wei, et al.
Publicado: (2018)

Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase
por: Yi, Jia, et al.
Publicado: (2022)

A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models
por: Burgess, Jeremy D., et al.
Publicado: (2023)

A mutant methionyl-tRNA synthetase-based toolkit to assess induced-mesenchymal stromal cell secretome in mixed-culture disease models
por: Burgess, Jeremy D., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7qbai113l7m5niv3n97pfsdi3g