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Synthetic hydrophobic peptides derived from MgtR weaken Salmonella pathogenicity and work with a different mode of action than endogenously produced peptides

Due to the antibiotic resistance crisis, novel therapeutic strategies need to be developed against bacterial pathogens. Hydrophobic bacterial peptides (small proteins under 50 amino acids) have emerged as regulatory molecules that can interact with bacterial membrane proteins to modulate their activ...

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Detalles Bibliográficos
Autores principales: Olvera, Mariana Rosas, Garai, Preeti, Mongin, Grégoire, Vivès, Eric, Gannoun-Zaki, Laila, Blanc-Potard, Anne-Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813294/
https://www.ncbi.nlm.nih.gov/pubmed/31649255
http://dx.doi.org/10.1038/s41598-019-51760-2