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Structural transitions during the scaffolding-driven assembly of a viral capsid

Assembly of tailed bacteriophages and herpesviruses starts with formation of procapsids (virion precursors without DNA). Scaffolding proteins (SP) drive assembly by chaperoning the major capsid protein (MCP) to build an icosahedral lattice. Here we report near-atomic resolution cryo-EM structures of...

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Detalles Bibliográficos
Autores principales:	Ignatiou, Athanasios, Brasilès, Sandrine, El Sadek Fadel, Mehdi, Bürger, Jörg, Mielke, Thorsten, Topf, Maya, Tavares, Paulo, Orlova, Elena V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813328/ https://www.ncbi.nlm.nih.gov/pubmed/31649265 http://dx.doi.org/10.1038/s41467-019-12790-6

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