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Bases of Bacterial Sodium Channel Selectivity Among Organic Cations

Hille’s (1971) seminal study of organic cation selectivity of eukaryotic voltage-gated sodium channels showed a sharp size cut-off for ion permeation, such that no ion possessing a methyl group was permeant. Using the prokaryotic channel, NaChBac, we found some similarity and two peculiar difference...

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Detalles Bibliográficos
Autores principales: Wang, Yibo, Finol-Urdaneta, Rocio K., Ngo, Van Anh, French, Robert J., Noskov, Sergei Yu.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813354/
https://www.ncbi.nlm.nih.gov/pubmed/31649292
http://dx.doi.org/10.1038/s41598-019-51605-y