High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease

Background: Chronic granulomatous disease (CGD) is caused by a malfunctioning nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex in phagocytes, leading to impaired bacterial and fungal killing and hyperinflammation. Objective: To characterize macrophage subsets and cytokine/chemokin...

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Detalles Bibliográficos
Autores principales: Meda Spaccamela, Virginia, Valencia, Rocio G., Pastukhov, Oleksandr, Duppenthaler, Andrea, Dettmer, Matthias S., Erb, Juliane, Steiner, Urs C., Hillinger, Sven, Speckmann, Carsten, Ehl, Stephan, Reichenbach, Janine, Siler, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813411/
https://www.ncbi.nlm.nih.gov/pubmed/31681257
http://dx.doi.org/10.3389/fimmu.2019.02236

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