Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome

Fragile X syndrome (FXS) is a neurodevelopmental disorder that causes intellectual disability, as well as the leading monogenic cause of autism spectrum disorders (ASD), in which neurons show aberrant dendritic spine structure. The reduction/absence of the functional FMRP protein, coded by the X-lin...

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Detalles Bibliográficos
Autores principales: Cheng, Ke, Chen, Yu-shan, Yue, Chao-xiong, Zhang, Si-ming, Pei, Ya-Ping, Cheng, Gui-rong, Liu, Dan, Xu, Lang, Dong, Hong-xin, Zeng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813673/
https://www.ncbi.nlm.nih.gov/pubmed/31680833
http://dx.doi.org/10.3389/fnins.2019.01098

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