Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report

Dipeptidyl peptidase-4 inhibitors (DPP-4i) are one of the mainstay drugs in the management of type 2 diabetes mellitus. It has been well-documented that these class of drugs cause allergic reactions. Bullous pemphigoid (BP) is a blistering skin condition commonly associated with many drugs. Here, we...

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Detalles Bibliográficos
Autores principales: Karthik, S, Joseph, PE, Babu, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813680/
https://www.ncbi.nlm.nih.gov/pubmed/31535624
http://dx.doi.org/10.4103/jpgm.JPGM_120_19
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author Karthik, S
Joseph, PE
Babu, T
author_facet Karthik, S
Joseph, PE
Babu, T
author_sort Karthik, S
collection PubMed
description Dipeptidyl peptidase-4 inhibitors (DPP-4i) are one of the mainstay drugs in the management of type 2 diabetes mellitus. It has been well-documented that these class of drugs cause allergic reactions. Bullous pemphigoid (BP) is a blistering skin condition commonly associated with many drugs. Here, we report a case of probable DPP-4i-induced BP in an elderly man, which resolved on discontinuation of the drug. Although this adverse drug reaction has been documented in Western world and Japanese ethnicity, this seems to be the first case report of such occurrence in Indian ethnicity.
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spelling pubmed-68136802019-10-31 Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report Karthik, S Joseph, PE Babu, T J Postgrad Med Case Report Dipeptidyl peptidase-4 inhibitors (DPP-4i) are one of the mainstay drugs in the management of type 2 diabetes mellitus. It has been well-documented that these class of drugs cause allergic reactions. Bullous pemphigoid (BP) is a blistering skin condition commonly associated with many drugs. Here, we report a case of probable DPP-4i-induced BP in an elderly man, which resolved on discontinuation of the drug. Although this adverse drug reaction has been documented in Western world and Japanese ethnicity, this seems to be the first case report of such occurrence in Indian ethnicity. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6813680/ /pubmed/31535624 http://dx.doi.org/10.4103/jpgm.JPGM_120_19 Text en Copyright: © 2019 Journal of Postgraduate Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Karthik, S
Joseph, PE
Babu, T
Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report
title Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report
title_full Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report
title_fullStr Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report
title_full_unstemmed Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report
title_short Bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – A case report
title_sort bullous pemphigoid associated with dipeptidyl peptidase-4 inhibitor – a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813680/
https://www.ncbi.nlm.nih.gov/pubmed/31535624
http://dx.doi.org/10.4103/jpgm.JPGM_120_19
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AT babut bullouspemphigoidassociatedwithdipeptidylpeptidase4inhibitoracasereport

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