Melanoma-Derived Exosomes Induce PD-1 Overexpression and Tumor Progression via Mesenchymal Stem Cell Oncogenic Reprogramming

Recently, it has been described that programmed cell death protein 1 (PD-1) overexpressing melanoma cells are highly aggressive. However, until now it has not been defined which factors lead to the generation of PD-1 overexpressing subpopulations. Here, we present that melanoma-derived exosomes, con...

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Detalles Bibliográficos
Autores principales: Gyukity-Sebestyén, Edina, Harmati, Mária, Dobra, Gabriella, Németh, István B., Mihály, Johanna, Zvara, Ágnes, Hunyadi-Gulyás, Éva, Katona, Róbert, Nagy, István, Horváth, Péter, Bálind, Árpád, Szkalisity, Ábel, Kovács, Mária, Pankotai, Tibor, Borsos, Barbara, Erdélyi, Miklós, Szegletes, Zsolt, Veréb, Zoltán J., Buzás, Edit I., Kemény, Lajos, Bíró, Tamás, Buzás, Krisztina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813737/
https://www.ncbi.nlm.nih.gov/pubmed/31681332
http://dx.doi.org/10.3389/fimmu.2019.02459

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