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Association of Sperm Methylation at LINE-1, Four Candidate Genes, and Nicotine/Alcohol Exposure With the Risk of Infertility

In this study, we examined whether smoking and drinking affect sperm quality and the DNA methylation of the repetitive element LINE-1, MEST, P16, H19, and GNAS in sperm. Semen samples were obtained from 143 male residents in a minority-inhabited district of Guizhou province in southwest China. Quant...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjing, Li, Min, Sun, Feng, Xu, Xuting, Zhang, Zhaofeng, Liu, Junwei, Sun, Xiaowei, Zhang, Aiping, Shen, Yupei, Xu, Jianhua, Miao, Maohua, Wu, Bin, Yuan, Yao, Huang, Xianliang, Shi, Huijuan, Du, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813923/
https://www.ncbi.nlm.nih.gov/pubmed/31681430
http://dx.doi.org/10.3389/fgene.2019.01001