Enhanced Bruton’s tyrosine kinase in B-cells and autoreactive IgA in patients with idiopathic pulmonary fibrosis

RATIONALE: Idiopathic Pulmonary Fibrosis (IPF) is thought to be triggered by repeated alveolar epithelial cell injury. Current evidence suggests that aberrant immune activation may contribute. However, the role of B-cell activation remains unclear. We determined the phenotype and activation status o...

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Detalles Bibliográficos
Autores principales: Heukels, Peter, van Hulst, Jennifer A. C., van Nimwegen, Menno, Boorsma, Carian E., Melgert, Barbro N., von der Thusen, Jan H., van den Blink, Bernt, Hoek, Rogier A. S., Miedema, Jelle R., Neys, Stefan F. H., Corneth, Odilia B. J., Hendriks, Rudi W., Wijsenbeek, Marlies S., Kool, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814043/
https://www.ncbi.nlm.nih.gov/pubmed/31651327
http://dx.doi.org/10.1186/s12931-019-1195-7

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