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The Cytotoxic Effects of Geranylgeranylacetone Are Attenuated in the High-Glucose Condition

Geranylgeranylacetone (GGA) has been used as an antiulcer drug and also is known as inducer of heat shock protein 70 that has cytoprotective effects especially in hyperglycemic condition. In contrast, cytotoxicity of GGA has also been reported. Some studies have reported that GGA suppresses cell gro...

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Detalles Bibliográficos
Autores principales: Nakano, Yuko, Kobayashi, Daisuke, Miyake, Masao, Kanno, Ryoko, Murakawa, Masahiro, Hazama, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814082/
https://www.ncbi.nlm.nih.gov/pubmed/31656692
http://dx.doi.org/10.1089/biores.2018.0041

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