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An In Vitro Human Segmentation Clock Model Derived from Embryonic Stem Cells
Defects in somitogenesis result in vertebral malformations at birth known as spondylocostal dysostosis (SCDO). Somites are formed with a species-specific periodicity controlled by the “segmentation clock,” which comprises a group of oscillatory genes in the presomitic mesoderm. Here, we report that...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814198/ https://www.ncbi.nlm.nih.gov/pubmed/31461642 http://dx.doi.org/10.1016/j.celrep.2019.07.090 |