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Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study

AIM: Urinary flow after urethroplasty is of paramount importance. The aim of this study is to evaluate the progression of uroflowmetry (UF) parameters after different distal and proximal hypospadias repair techniques. METHODS: In this cohort study, cases that underwent primary hypospadias repair at...

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Autores principales: Al Adl, Ahmed Mahmoud, Omar, Rabea Gomaa, Mohey, Ahmed, El Mogy, Ahmed Abd El Naeem, El Karamany, Tarek Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814353/
https://www.ncbi.nlm.nih.gov/pubmed/31696095
http://dx.doi.org/10.2147/RRU.S227601
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author Al Adl, Ahmed Mahmoud
Omar, Rabea Gomaa
Mohey, Ahmed
El Mogy, Ahmed Abd El Naeem
El Karamany, Tarek Mohammed
author_facet Al Adl, Ahmed Mahmoud
Omar, Rabea Gomaa
Mohey, Ahmed
El Mogy, Ahmed Abd El Naeem
El Karamany, Tarek Mohammed
author_sort Al Adl, Ahmed Mahmoud
collection PubMed
description AIM: Urinary flow after urethroplasty is of paramount importance. The aim of this study is to evaluate the progression of uroflowmetry (UF) parameters after different distal and proximal hypospadias repair techniques. METHODS: In this cohort study, cases that underwent primary hypospadias repair at our institution between March 2010 and December 2018 were included when uncomplicated, asymptomatic and toilet-trained. UF findings and post void residual were described after each specific technique. RESULTS: In all, 88 patients were eligible. Time to last UF ranged from 35 to 138 months postoperatively. Significant increase started 36 months after distal tubularized incised plate urethroplasty (TIP) and afterwards than Mathieu technique. While was noticed 24 and 36 months after Onlay technique and proximal TIP, respectively; however, TIP showed steady significant increase atall time intervals. Duckett repair exhibited insignificant change in maximum flow rate (Qmax) values, buccal mucosal graft (BMG) and inner preputial graft (IPG), significant increase in the Qmax values after 6 and 24 months, respectively, then remained steady high. Transposed preputial flap (TPF) showed significant increase at 6–12 months only, then remained steady lower than the other two techniques. Obstructed flow was 37% after distal TIP, 30% after Mathieu, 25% after proximal TIP, 66.7% after Duckett repair, and 33.3% after TPF. There were no obstructed cases after BMG and IPG. DISCUSSION: Improvement by time varied between techniques. After repair most cases are below the 50th percentile, implying that the reconstructed urethra is not functioning as a normal urethra. Staged repair for proximal hypospadias is preferable to a heroic one-stage procedure. CONCLUSION: Choice of the surgical technique for hypospadias repair had impact on the improvement of Qmax values. TIP improved 36 months postoperatively. However, for proximal cases staged graft repair had earlier improvement and higher Qmax values than proximal TIP and Onlay techniques.
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spelling pubmed-68143532019-11-06 Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study Al Adl, Ahmed Mahmoud Omar, Rabea Gomaa Mohey, Ahmed El Mogy, Ahmed Abd El Naeem El Karamany, Tarek Mohammed Res Rep Urol Original Research AIM: Urinary flow after urethroplasty is of paramount importance. The aim of this study is to evaluate the progression of uroflowmetry (UF) parameters after different distal and proximal hypospadias repair techniques. METHODS: In this cohort study, cases that underwent primary hypospadias repair at our institution between March 2010 and December 2018 were included when uncomplicated, asymptomatic and toilet-trained. UF findings and post void residual were described after each specific technique. RESULTS: In all, 88 patients were eligible. Time to last UF ranged from 35 to 138 months postoperatively. Significant increase started 36 months after distal tubularized incised plate urethroplasty (TIP) and afterwards than Mathieu technique. While was noticed 24 and 36 months after Onlay technique and proximal TIP, respectively; however, TIP showed steady significant increase atall time intervals. Duckett repair exhibited insignificant change in maximum flow rate (Qmax) values, buccal mucosal graft (BMG) and inner preputial graft (IPG), significant increase in the Qmax values after 6 and 24 months, respectively, then remained steady high. Transposed preputial flap (TPF) showed significant increase at 6–12 months only, then remained steady lower than the other two techniques. Obstructed flow was 37% after distal TIP, 30% after Mathieu, 25% after proximal TIP, 66.7% after Duckett repair, and 33.3% after TPF. There were no obstructed cases after BMG and IPG. DISCUSSION: Improvement by time varied between techniques. After repair most cases are below the 50th percentile, implying that the reconstructed urethra is not functioning as a normal urethra. Staged repair for proximal hypospadias is preferable to a heroic one-stage procedure. CONCLUSION: Choice of the surgical technique for hypospadias repair had impact on the improvement of Qmax values. TIP improved 36 months postoperatively. However, for proximal cases staged graft repair had earlier improvement and higher Qmax values than proximal TIP and Onlay techniques. Dove 2019-10-21 /pmc/articles/PMC6814353/ /pubmed/31696095 http://dx.doi.org/10.2147/RRU.S227601 Text en © 2019 Al Adl et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Al Adl, Ahmed Mahmoud
Omar, Rabea Gomaa
Mohey, Ahmed
El Mogy, Ahmed Abd El Naeem
El Karamany, Tarek Mohammed
Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study
title Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study
title_full Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study
title_fullStr Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study
title_full_unstemmed Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study
title_short Chronological Changes In Uroflowmetry After Hypospadias Repair: An Observational Study
title_sort chronological changes in uroflowmetry after hypospadias repair: an observational study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814353/
https://www.ncbi.nlm.nih.gov/pubmed/31696095
http://dx.doi.org/10.2147/RRU.S227601
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