Disulfiram suppressed ethanol promoted RANKL-induced osteoclastogenesis in vitro and ethanol-induced osteoporosis in vivo via ALDH1A1-NFATc1 axis

Excessive alcohol consumption is positively related to osteoporosis, and its treatment strategies are poorly developed. Disulfiram inhibits receptor activator of nuclear factor kappa-B ligand (RANKL)-induced osteoclastogenesis; however, whether it can be used for ethanol-induced osteoclastogenesis a...

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Detalles Bibliográficos
Autores principales: Jia, Yewei, Jiang, Jiawei, Zhao, Kangxian, Zhang, Tan, Sun, Peng, Peng, Jiaxuan, Yang, Qichang, Qian, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814600/
https://www.ncbi.nlm.nih.gov/pubmed/31596733
http://dx.doi.org/10.18632/aging.102279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814600/
https://www.ncbi.nlm.nih.gov/pubmed/31596733
http://dx.doi.org/10.18632/aging.102279

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