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Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop

Osteoarthritis (OA) is the most common degenerative joint disease and involves the loss of articular cartilage integrity, formation of articular osteophytes, remodeling of subchondral bone, and synovitis. Knockdown of receptor interacting serine/threonine kinase (RIPK) 1 leads to anti-inflammatory a...

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Detalles Bibliográficos
Autores principales: Liang, Shuang, Wang, Zheng-Gang, Zhang, Zhen-Zhen, Chen, Kun, Lv, Zheng-Tao, Wang, Yu-Ting, Cheng, Peng, Sun, Kai, Yang, Qing, Chen, An-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814603/
https://www.ncbi.nlm.nih.gov/pubmed/31606726
http://dx.doi.org/10.18632/aging.102354