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Decreased RIPK1 expression in chondrocytes alleviates osteoarthritis via the TRIF/MyD88-RIPK1-TRAF2 negative feedback loop
Osteoarthritis (OA) is the most common degenerative joint disease and involves the loss of articular cartilage integrity, formation of articular osteophytes, remodeling of subchondral bone, and synovitis. Knockdown of receptor interacting serine/threonine kinase (RIPK) 1 leads to anti-inflammatory a...
Autores principales: | Liang, Shuang, Wang, Zheng-Gang, Zhang, Zhen-Zhen, Chen, Kun, Lv, Zheng-Tao, Wang, Yu-Ting, Cheng, Peng, Sun, Kai, Yang, Qing, Chen, An-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814603/ https://www.ncbi.nlm.nih.gov/pubmed/31606726 http://dx.doi.org/10.18632/aging.102354 |
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