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Decreased levels of circulating trimethylamine N-oxide alleviate cognitive and pathological deterioration in transgenic mice: a potential therapeutic approach for Alzheimer’s disease

Trimethylamine-N-oxide (TMAO), a metabolite of gut microbiota, has been implicated in the pathogenesis of Alzheimer’s disease (AD). However, the mechanisms by which TMAO influence cognitive and pathological processes in the AD have not been investigated. In this study, we found that the circulating...

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Detalles Bibliográficos
Autores principales: Gao, Qiang, Wang, Yuan, Wang, Xin, Fu, Shuang, Zhang, Xin, Wang, Rui-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814608/
https://www.ncbi.nlm.nih.gov/pubmed/31612864
http://dx.doi.org/10.18632/aging.102352