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TRIM59 loss in M2 macrophages promotes melanoma migration and invasion by upregulating MMP-9 and Madcam1
The culture supernatant from macrophages overexpressing TRIM59 has a cytotoxic effect on melanoma, but the mechanism remains unclear. To investigate whether deletion of TRIM59 in macrophages affects the metastatic potential of melanoma cells, we polarized control and TRIM59-deficient bone marrow-der...
Autores principales: | Tian, Yuan, Guo, Yantong, Zhu, Pei, Zhang, Dongxu, Liu, Shanshan, Tang, Mengyan, Wang, Yuanxin, Jin, Zheng, Li, Dong, Yan, Dongmei, Li, Guiying, Zhu, Xun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814609/ https://www.ncbi.nlm.nih.gov/pubmed/31600735 http://dx.doi.org/10.18632/aging.102351 |
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