Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats

Obesity has been identified with an expanded danger of a progression of illnesses that include different organ-frameworks of the body. In the present examination, we evaluated the hypolipidemic properties of Echinochrome (Ech) pigment in a high-fat diet (HFD) induced hyperlipidemia in rats. After th...

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Detalles Bibliográficos
Autores principales: Fahmy, Sohair R., Zaki, Nashwah Ismail, Eid, Shaimaa Zakaria, Mohamed, Ayman Saber, Hassanein, Sarah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814671/
https://www.ncbi.nlm.nih.gov/pubmed/31628663
http://dx.doi.org/10.1007/s13659-019-00221-4
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author Fahmy, Sohair R.
Zaki, Nashwah Ismail
Eid, Shaimaa Zakaria
Mohamed, Ayman Saber
Hassanein, Sarah S.
author_facet Fahmy, Sohair R.
Zaki, Nashwah Ismail
Eid, Shaimaa Zakaria
Mohamed, Ayman Saber
Hassanein, Sarah S.
author_sort Fahmy, Sohair R.
collection PubMed
description Obesity has been identified with an expanded danger of a progression of illnesses that include different organ-frameworks of the body. In the present examination, we evaluated the hypolipidemic properties of Echinochrome (Ech) pigment in a high-fat diet (HFD) induced hyperlipidemia in rats. After the hyperlipidemic model was set up, rats were haphazardly separated into five groups as follows: normal control group, HFD group, Atorvastatin (ATOR) group (80 mg/kg), Ech group (1 mg/kg) and combined group ATOR + Ech. The outcomes demonstrated that Ech improves lipid profile, liver functions, kidney functions and antioxidant markers of obese rats. The findings of the present investigation indicated that the Ech possesses hypolipidemic potential in obese rats.
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spelling pubmed-68146712019-11-08 Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats Fahmy, Sohair R. Zaki, Nashwah Ismail Eid, Shaimaa Zakaria Mohamed, Ayman Saber Hassanein, Sarah S. Nat Prod Bioprospect Original Article Obesity has been identified with an expanded danger of a progression of illnesses that include different organ-frameworks of the body. In the present examination, we evaluated the hypolipidemic properties of Echinochrome (Ech) pigment in a high-fat diet (HFD) induced hyperlipidemia in rats. After the hyperlipidemic model was set up, rats were haphazardly separated into five groups as follows: normal control group, HFD group, Atorvastatin (ATOR) group (80 mg/kg), Ech group (1 mg/kg) and combined group ATOR + Ech. The outcomes demonstrated that Ech improves lipid profile, liver functions, kidney functions and antioxidant markers of obese rats. The findings of the present investigation indicated that the Ech possesses hypolipidemic potential in obese rats. Springer Singapore 2019-10-18 /pmc/articles/PMC6814671/ /pubmed/31628663 http://dx.doi.org/10.1007/s13659-019-00221-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Fahmy, Sohair R.
Zaki, Nashwah Ismail
Eid, Shaimaa Zakaria
Mohamed, Ayman Saber
Hassanein, Sarah S.
Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats
title Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats
title_full Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats
title_fullStr Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats
title_full_unstemmed Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats
title_short Effectiveness of Echinochrome on HFD-Induced Hyperlipidemia in Rats
title_sort effectiveness of echinochrome on hfd-induced hyperlipidemia in rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814671/
https://www.ncbi.nlm.nih.gov/pubmed/31628663
http://dx.doi.org/10.1007/s13659-019-00221-4
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