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Comparing modes of delivery of a combination of ion channel inhibitors for limiting secondary degeneration following partial optic nerve transection

Injury to the central nervous system is exacerbated by secondary degeneration. Previous research has shown that a combination of orally and locally administered ion channel inhibitors following partial optic nerve injury protects the myelin sheath and preserves function in the ventral optic nerve, v...

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Detalles Bibliográficos
Autores principales: Toomey, Lillian M., Bartlett, Carole A., Gavriel, Nikolas, McGonigle, Terence, Majimbi, Maimuna, Gopalasingam, Gopana, Rodger, Jennifer, Fitzgerald, Melinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814709/
https://www.ncbi.nlm.nih.gov/pubmed/31653948
http://dx.doi.org/10.1038/s41598-019-51886-3