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Depletion of Mitochondrial DNA in Differentiated Retinal Pigment Epithelial Cells
We investigated the effects of treating differentiated retinal pigment epithelial (RPE) cells with didanosine (ddI), which is associated with retinopathy in individuals with HIV/AIDS. We hypothesized that such treatment would cause depletion of mitochondrial DNA and provide insight into the conseque...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814719/ https://www.ncbi.nlm.nih.gov/pubmed/31653972 http://dx.doi.org/10.1038/s41598-019-51761-1 |