Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program

Herpesvirus infection initiates a range of perturbations in the host cell, which remain poorly understood at the level of individual cells. Here, we quantify the transcriptome of single human primary fibroblasts during the first hours of lytic infection with HSV-1. By applying a generalizable analys...

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Detalles Bibliográficos
Autores principales: Wyler, Emanuel, Franke, Vedran, Menegatti, Jennifer, Kocks, Christine, Boltengagen, Anastasiya, Praktiknjo, Samantha, Walch-Rückheim, Barbara, Bosse, Jens, Rajewsky, Nikolaus, Grässer, Friedrich, Akalin, Altuna, Landthaler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814756/
https://www.ncbi.nlm.nih.gov/pubmed/31653857
http://dx.doi.org/10.1038/s41467-019-12894-z

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