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Tau deposition is associated with functional isolation of the hippocampus in aging

The tau protein aggregates in aging and Alzheimer disease and may lead to memory loss through disruption of medial temporal lobe (MTL)-dependent memory systems. Here, we investigated tau-mediated mechanisms of hippocampal dysfunction that underlie the expression of episodic memory decline using fMRI...

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Detalles Bibliográficos
Autores principales:	Harrison, Theresa M., Maass, Anne, Adams, Jenna N., Du, Richard, Baker, Suzanne L., Jagust, William J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814780/ https://www.ncbi.nlm.nih.gov/pubmed/31653847 http://dx.doi.org/10.1038/s41467-019-12921-z

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