Computational Analysis of Insulin-Glucagon Signalling Network: Implications of Bistability to Metabolic Homeostasis and Disease states

Insulin and glucagon control plasma macronutrient homeostasis through their signalling network composed of multiple feedback and crosstalk interactions. To understand how these interactions contribute to metabolic homeostasis and disease states, we analysed the steady state response of metabolic reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Somvanshi, Pramod R., Tomar, Manu, Kareenhalli, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814820/
https://www.ncbi.nlm.nih.gov/pubmed/31653897
http://dx.doi.org/10.1038/s41598-019-50889-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814820/
https://www.ncbi.nlm.nih.gov/pubmed/31653897
http://dx.doi.org/10.1038/s41598-019-50889-4

Ejemplares similares