TET2-interacting long noncoding RNA promotes active DNA demethylation of the MMP-9 promoter in diabetic wound healing

Wound healing in diabetic skin is impaired by excessive activation of matrix metalloproteinase-9 (MMP-9). MMP-9 transcription is activated by Ten-eleven translocation 2 (TET2), a well-known DNA demethylation protein that induces MMP-9 promoter demethylation in diabetic skin tissues. However, how TET...

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Detalles Bibliográficos
Autores principales: Zhou, Liyan, Ren, Meng, Zeng, Tingting, Wang, Wei, Wang, Xiaoyi, Hu, Mengdie, Su, Shicheng, Sun, Kan, Wang, Chuan, Liu, Jing, Yang, Chuan, Yan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814823/
https://www.ncbi.nlm.nih.gov/pubmed/31653825
http://dx.doi.org/10.1038/s41419-019-2047-6

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