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The PPAR-γ antagonist T007 inhibits RANKL-induced osteoclastogenesis and counteracts OVX-induced bone loss in mice

BACKGROUND: Osteoclasts are key determinant cellular components implicated in the development and progression of disorders driven by bone damage. Herein, we studied the upshot of T007, an antagonist of peroxisome proliferator-activated receptor-gamma (PPARγ), on osteoclastogenesis using cell and ani...

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Detalles Bibliográficos
Autores principales:	Li, Xiang, Ning, Lei, Ma, Jianjun, Xie, Ziang, Zhao, Xiangde, Wang, Gangliang, Wan, Xinyu, Qiu, Pengcheng, Yao, Teng, Wang, Haoming, Fan, Shunwu, Wan, Shuanglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815399/ https://www.ncbi.nlm.nih.gov/pubmed/31655621 http://dx.doi.org/10.1186/s12964-019-0442-3

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