Protective mechanism of artemisinin on rat bone marrow-derived mesenchymal stem cells against apoptosis induced by hydrogen peroxide via activation of c-Raf-Erk1/2-p90(rsk)-CREB pathway

BACKGROUND: Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is one of the new therapeutic strategies for treating ischemic brain and heart tissues. However, the poor survival rate of transplanted BMSCs in ischemic tissue, due to high levels of reactive oxygen species (ROS), limits t...

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Detalles Bibliográficos
Autores principales: Fang, Jiankang, Zhao, Xia, Li, Shuai, Xing, Xingan, Wang, Haitao, Lazarovici, Philip, Zheng, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815409/
https://www.ncbi.nlm.nih.gov/pubmed/31655619
http://dx.doi.org/10.1186/s13287-019-1419-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815409/
https://www.ncbi.nlm.nih.gov/pubmed/31655619
http://dx.doi.org/10.1186/s13287-019-1419-2

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