Peptide Deformylase (def) is essential in Mycobacterium smegmatis, but the essentiality is compensated by inactivation of methionine formylation

BACKGROUND: Co-translational processes in bacteria are attractive drug targets, but while some processes are essential, others are not. The essentiality of Peptide Deformylase (PDF, def) for vitality of mycobacteria was speculated, but never unequivocally proven. RESULTS: Here we show by targeted de...

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Detalles Bibliográficos
Autores principales: Naor, Noga, Gadot, Omer, Meir, Michal, Barkan, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815462/
https://www.ncbi.nlm.nih.gov/pubmed/31655553
http://dx.doi.org/10.1186/s12866-019-1611-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815462/
https://www.ncbi.nlm.nih.gov/pubmed/31655553
http://dx.doi.org/10.1186/s12866-019-1611-7

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