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Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation

The cellular and molecular mechanisms underlying loss of muscle mass with age (sarcopenia) are not well-understood; however, heterochronic parabiosis experiments show that circulating factors are likely to play a role. Kynurenine (KYN) is a circulating tryptophan metabolite that is known to increase...

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Detalles Bibliográficos
Autores principales:	Kaiser, Helen, Yu, Kanglun, Pandya, Chirayu, Mendhe, Bharati, Isales, Carlos M., McGee-Lawrence, Meghan E., Johnson, Maribeth, Fulzele, Sadanand, Hamrick, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815546/ https://www.ncbi.nlm.nih.gov/pubmed/31737181 http://dx.doi.org/10.1155/2019/9894238

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