Cargando…

Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis

Osteoarthritis (OA) is an age-related degenerative disease with complicated pathology involving chondrocyte apoptosis and extracellular matrix (ECM) degradation. Previous studies have shown that moderate autophagy has a protective effect against apoptosis in chondrocyte. Mangiferin is a natural poly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yao, Wu, Yaosen, Jiang, Kaixia, Han, Wen, Zhang, Jing, Xie, Lin, Liu, Yanlong, Xiao, Jian, Wang, Xiangyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815628/ https://www.ncbi.nlm.nih.gov/pubmed/31885823 http://dx.doi.org/10.1155/2019/8783197

Ejemplares similares

Silencing ATF3 Might Delay TBHP-Induced Intervertebral Disc Degeneration by Repressing NPC Ferroptosis, Apoptosis, and ECM Degradation
por: Li, Yongjin, et al.
Publicado: (2022)

“Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300”
por: Borzì, Rosa Maria, et al.
Publicado: (2019)

Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300
por: Sacitharan, Pradeep K., et al.
Publicado: (2018)

The effect of mangiferin on skin: Penetration, permeation and inhibition of ECM enzymes
por: Ochocka, Renata, et al.
Publicado: (2017)

Vicenin 3 ameliorates ECM degradation by regulating the MAPK pathway in SW1353 chondrocytes
por: Chen, Yue-Yuan, et al.
Publicado: (2021)

Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis
por: Kong, Jinsong, et al.
Publicado: (2020)

Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy
por: Sun, Kai, et al.
Publicado: (2023)

Effect of electromagnetic fields on human osteoarthritic and non-osteoarthritic chondrocytes
por: Redeker, Julia Isabelle, et al.
Publicado: (2017)

Corosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis
por: Han, Hui, et al.
Publicado: (2022)

Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2
por: Jin, Jie, et al.
Publicado: (2021)

Dual Role of SIRT1 in Autophagy and Lipid Metabolism Regulation in Osteoarthritic Chondrocytes
por: Papageorgiou, Aliki-Alexandra, et al.
Publicado: (2021)

Ethanolic Extract of Propolis Modulates Autophagy-Related microRNAs in Osteoarthritic Chondrocytes
por: Arias, Consuelo, et al.
Publicado: (2023)

Xanthohumol Attenuated Inflammation and ECM Degradation by Mediating HO-1/C/EBPβ Pathway in Osteoarthritis Chondrocytes
por: Zhang, Ming, et al.
Publicado: (2021)

Spermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300: response to correspondence by Borzì et al.
por: Sacitharan, Pradeep K., et al.
Publicado: (2019)

Identification of the calcitonin receptor in osteoarthritic chondrocytes
por: Segovia-Silvestre, Toni, et al.
Publicado: (2011)

Irisin Recovers Osteoarthritic Chondrocytes In Vitro
por: Vadalà, Gianluca, et al.
Publicado: (2020)

MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint
por: Yang, Hongxu, et al.
Publicado: (2019)

OPN inhibits autophagy through CD44, integrin and the MAPK pathway in osteoarthritic chondrocytes
por: Bai, Rui-Jun, et al.
Publicado: (2022)

Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy
por: Shen, Zhonghai, et al.
Publicado: (2021)

Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis
por: Musumeci, Giuseppe, et al.
Publicado: (2015)

SPRY4 acts as an indicator of osteoarthritis severity and regulates chondrocyte hypertrophy and ECM protease expression
por: Park, Sunghyun, et al.
Publicado: (2021)

SIRT1 restoration enhances chondrocyte autophagy in osteoarthritis through PTEN-mediated EGFR ubiquitination
por: Lu, Qunshan, et al.
Publicado: (2022)

Rat Chondrocyte Inflammation and Osteoarthritis Are Ameliorated by Madecassoside
por: Moqbel, Safwat Adel Abdo, et al.
Publicado: (2020)

Cell biology and functional genomics of osteoarthritic chondrocytes
por: Aigner, T, et al.
Publicado: (2003)

The effect of resveratrol on normal and osteoarthritic chondrocyte metabolism
por: Kim, H. J., et al.
Publicado: (2014)

Biological Effects of Phosphocitrate on Osteoarthritic Articular Chondrocytes
por: Sun, Yubo, et al.
Publicado: (2017)

Modulated Autophagy by MicroRNAs in Osteoarthritis Chondrocytes
por: Yu, Yinghao, et al.
Publicado: (2019)

Navitoclax (ABT263) reduces inflammation and promotes chondrogenic phenotype by clearing senescent osteoarthritic chondrocytes in osteoarthritis
por: Yang, Hao, et al.
Publicado: (2020)

Up-regulation of P21-activated kinase 1 in osteoarthritis chondrocytes is responsible for osteoarthritic cartilage destruction
por: Ma, Wanli, et al.
Publicado: (2020)

Wogonoside inhibits IL-1β induced catabolism and hypertrophy in mouse chondrocyte and ameliorates murine osteoarthritis
por: Tang, Qian, et al.
Publicado: (2017)

High glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes
por: Wang, Ben, et al.
Publicado: (2021)

Mangiferin Ameliorates Obesity-Associated Inflammation and Autophagy in High-Fat-Diet-Fed Mice: In Silico and In Vivo Approaches
por: Noh, Ji-Won, et al.
Publicado: (2022)

The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes
por: Gao, Yue, et al.
Publicado: (2014)

Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis
por: Pei, Wenbin, et al.
Publicado: (2021)

Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway
por: Yao, Minjun, et al.
Publicado: (2022)

ECM signals ECM degradation
por: Powell, Kendall
Publicado: (2006)

Proliferation and differentiation potential of chondrocytes from osteoarthritic patients
por: Tallheden, Tommi, et al.
Publicado: (2005)

Toll-like receptors in human chondrocytes and osteoarthritic cartilage
por: Sillat, Tarvo, et al.
Publicado: (2013)

Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis
por: Ren, Chenghao, et al.
Publicado: (2021)

Anti-Osteoarthritic Effects of Antarctic Krill Oil in Primary Chondrocytes and a Surgical Rat Model of Knee Osteoarthritis
por: Ku, Sae-Kwang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kpfk6eragn8f782tj0j35sfeop