Methyloleanolate Induces Apoptotic And Autophagic Cell Death Via Reactive Oxygen Species Generation And c-Jun N-terminal Kinase Phosphorylation

BACKGROUND: To develop a potent anticancer agent similar to oleanolate, the underlying mechanisms of its derivative, methyloleanolate, in the apoptosis and autophagy of A549 and H1299 cells were elucidated. PURPOSE: The aim of the present study was to investigate the effect of methyloleanolate in in...

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Detalles Bibliográficos
Autores principales: Jeong, Myoung Seok, Jung, Ji Hoon, Lee, Hyemin, Kim, Chang Geun, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815788/
https://www.ncbi.nlm.nih.gov/pubmed/31695422
http://dx.doi.org/10.2147/OTT.S211904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815788/
https://www.ncbi.nlm.nih.gov/pubmed/31695422
http://dx.doi.org/10.2147/OTT.S211904

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