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Methyloleanolate Induces Apoptotic And Autophagic Cell Death Via Reactive Oxygen Species Generation And c-Jun N-terminal Kinase Phosphorylation

BACKGROUND: To develop a potent anticancer agent similar to oleanolate, the underlying mechanisms of its derivative, methyloleanolate, in the apoptosis and autophagy of A549 and H1299 cells were elucidated. PURPOSE: The aim of the present study was to investigate the effect of methyloleanolate in in...

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Detalles Bibliográficos
Autores principales:	Jeong, Myoung Seok, Jung, Ji Hoon, Lee, Hyemin, Kim, Chang Geun, Kim, Sung-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815788/ https://www.ncbi.nlm.nih.gov/pubmed/31695422 http://dx.doi.org/10.2147/OTT.S211904

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