Construction of a replication-competent hepatitis B virus vector carrying secreted luciferase transgene and establishment of new hepatitis B virus replication and expression cell lines

BACKGROUND: Previously, we have successfully constructed replication-competent hepatitis B virus (HBV) vectors by uncoupling the P open reading frame (ORF) from the preC/C ORF to carefully design the transgene insertion site to overcome the compact organization of the HBV genome and maintain HBV rep...

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Detalles Bibliográficos
Autores principales: Ruan, Jie, Ping, Cai-Yan, Sun, Shuo, Cheng, Xin, Han, Peng-Yu, Zhang, Yin-Ge, Sun, Dian-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815792/
https://www.ncbi.nlm.nih.gov/pubmed/31660033
http://dx.doi.org/10.3748/wjg.v25.i39.5961

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