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DYRK1A inhibition suppresses STAT3/EGFR/Met signalling and sensitizes EGFR wild‐type NSCLC cells to AZD9291
DYRK1A is considered a potential cancer therapeutic target, but the role of DYRK1A in NSCLC oncogenesis and treatment requires further investigation. In our study, high DYRK1A expression was observed in tumour samples from patients with lung cancer compared with normal lung tissues, and the high lev...
Autores principales: | Li, Yang‐ling, Ding, Ke, Hu, Xiu, Wu, Lin‐wen, Zhou, Dong‐mei, Rao, Ming‐jun, Lin, Neng‐ming, Zhang, Chong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815810/ https://www.ncbi.nlm.nih.gov/pubmed/31454149 http://dx.doi.org/10.1111/jcmm.14609 |
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